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Difference Between RBCs and WBCs

May 29, 2023
written by Sidra Batool

The main difference between RBCs and WBCs is the difference of their function. RBCs are involved in oxygen transportation to body tissues, while WBCs help fight infection as part of the immune system.

image showing Difference Between RBCs and WBCs

RBC vs WBC

Here are the main differences between RBCs and WBCs:

CharacteristicRed Blood Cells (RBCs)White Blood Cells (WBCs)
Also known asErythrocytesLeucocytes
OriginLiver, spleen (embryonic phase), Red bone marrow (after birth)Red bone marrow, lymph nodes, spleen
Process of FormationErythropoiesisLeucopoiesis
AbundanceMore abundantLess abundant
SizeSmallerLarger
ShapeBiconcave disc-shapedIrregular or round
ColorPinkish-brownColorless
HemoglobinPresentAbsent
NucleusAbsentPresent
Circulatory SystemCardiovascular systemLymphatic system
TypesSingle typeMultiple types
Number IncrementIncreases in certain conditionsIncreases during infections
LifespanAverage lifespan of 120 daysLifespan ranges from 5-21 days
MotilityNon-motileMotile
MovementWithin cardiovascular systemBetween cardiovascular and lymphatic systems
Rouleaux FormationForms stacks or aggregationsDoes not form stacks or aggregations
Related DisordersAnemia, thalassemia, polycythemia vera, etc.Lymphoma, leukemia, myelodysplastic syndrome (MDS)
FunctionOxygen transport, blood viscosityDefense, phagocytosis, antibody production