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Differences Between DNA And RNA

May 29, 2023
written by Sidra Batool

The primary difference between DNA and RNA is the difference of sugar component and the type of nucleobase present. Firstly, RNA contains the sugar ribose, while DNA contains a modified version known as deoxyribose, which lacks one oxygen atom.

image showing Differences Between DNA And RNA
Here are the main differences between DNA and RNA:

DNA vs. RNA

Here are the main differences between DNA and RNA:

FactorsDNARNA
Full NameDeoxyribonucleic AcidRibonucleic Acid
Sugar ComponentDeoxyriboseRibose
StructureDouble-stranded helixMostly single-stranded
BasesAdenine (A), Thymine (T), Cytosine (C), Guanine (G)Adenine (A), Uracil (U), Cytosine (C), Guanine (G)
FunctionCarries genetic informationInvolved in protein synthesis and gene expression
LocationFound in the nucleusFound in the nucleus, cytoplasm, and ribosomes
StabilityMore stable and less prone to degradationLess stable and more prone to degradation
TypesGenomic DNA, mitochondrial DNA, plasmid DNA, etc.Messenger RNA (mRNA), transfer RNA (tRNA), ribosomal RNA (rRNA), etc.
ReplicationReplicates during cell divisionTranscribed from DNA during gene expression
Genetic CodeContains the complete genetic instructions for an organismTransfers the genetic information from DNA to synthesize proteins
Role in Protein SynthesisDNA serves as a template for RNA synthesis during transcriptionRNA molecules are involved in translation, transferring genetic information and assembling proteins